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A Clinically Relevant Radiation Delivery System in an Immunocompetent Rectal Cancer Murine Model to Study Tumorigenesis and the Tumor Microenvironment
Readouts should triangulate source and compartment: quantify superoxide with DHE-HPLC (particularly informative for NOX2), track H 2 O 2 with compartment-targeted HyPer sensors and couple these to endothelial function tests (e.g., flow-mediated dilation or wire myography), while avoiding nave reliance on raw probe fluorescence (see Small-molecule fluorescent/chemiluminescent probes section) that cannot disambiguate species or sources (Pak et al

Overall Efficacy of HPV-16/18 AS04-Adjuvanted Vaccine Against Grade 3 or Greater Cervical Intraepithelial Neoplasia: 4-Year End-of-Study Analysis of the Randomised, Double-Blind PATRICIA Trial
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