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Long-term histological evaluation shows negligible inflammatory infiltrates and normal hepatic and renal function after repeat dosing

Phase 2 clinical trials showed some positive outcomes, but these were not sufficiently significant over a treatment period of 7-10 days, leading to the halt of development [11, 12]

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Plant epigenomics for extenuation of abiotic stresses: Challenges and future perspectives

by apoptosis of intestinal epithelial cells in response to microbial infection, enables a proinflammatory environment including differentiation of autoreactive Th17 cells and other T helper cells 14