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Description
Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40
L.ShenM
Nature Communications (2025) 11
Some of the best sources are enriched ready-to-eat cereals made from whole grains, but the amount youll get varies from one brand to the next
This distinction matters because it means existing contamination still poses a risk
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