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Frequency: one subcutaneous injection each day at a fixed 2,330 mcg total-blend dose for 4 weeks, followed by a 24 week off period before any repeat cycle [3] [4]

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All of these versions of the model were fitted, and the estimated protective levels were very similar (Extended Data Fig

The peptide may also stimulate the expression of osteogenesis-related genes such as ALP, Bglap, and Runx2