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Preclinical models consistently show that combining serotonergic neuropeptides with SSRIs or MAOIs produces unpredictable neuromodulation that exceeds the therapeutic window of either agent alone

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The existence of DSIP-like peptides with similar biological activity has been hypothesized 5

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Suited for higher-dosage protocols (e.g., 600700 mcg daily) often split into 23 doses

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B12 is a naturally occurring nutrient from the B-vitamin family

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