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10.4161/cib.22872 Commun

The authors concluded that NAC resulted in improved performance suggestive of oxidative stress having a causal role in the fatigue process

doi: 10.1186/s40246-023-00561-w 7 DieterichWSchinkMZopfY

During the pre-stroke phase, sudden brain hypoxia damages the BBB, causing neuroinflammation, cytotoxic edema, production of reactive oxygen species, breakdown of tight junctions and the extracellular matrix, and increased BBB permeability