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Other cytokines, such as fibroblast growth factor (FGF) and hepatocyte growth factor (HGF), also act after inducing ROS, and ROS itself may affect growth factor receptor signaling, further promoting tumor development 63
In particular, GH hypersecretion leads to gigantism in childhood and acromegaly in adults, whereas congenital disruption of GH signaling causes short stature and in rare cases Laron syndrome

MN also contributed to the development of the manuscript

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A randomized, double-blind, placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome