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Recent advancements, exemplified by Tsai et al.'s development of an exosome-based mRNA vaccine for SARS-CoV-2, which effectively induced both cellular and humoral immune responses following intramuscular delivery, underscore the increasing promise of this platform

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Inflammatory bowel disease (IBD) patients exhibit altered gut microbial diversity, such as an imbalance between Firmicutes and Bacteroidetes , an increase in Proteobacteria , and the depletion of Roseburia species [31, 32]

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