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In subclinical PHT, increasing thyroid stimulating hormone (TSH) levels could be one of the causative factors intricate in the progression of cardiovascular complications including AS

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2004 Feb:44(3):153-59. [PMID: 14568558]

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It is recommended to take 2~3 samples to do a pre-experiment, diluting a series of diluent and determine the dilution factor when theinhibition ratiois 10%~50% (theoptimalinhibition ratio is the range of 25%~45%.) before formal experiment