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OS as end point or implied based on the known literature of the mouse model used

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In adults, bone development and bone loss are intricately linked and balanced through a continuous self-renewal process known as bone remodeling that ensures that bone mass and strength are maintained throughout life [2, 3]

Restoring NAD+ levels is one of the most promising areas of longevity research, particularly when combined with complementary metabolic compounds

doi: 10.3389/fmolb.2021.634874 258 RoldanGEGundersonLLNagorneyDMMartinJKIlstrupDMHolbrookMAet al

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