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Preclinical studies suggested that this system can induce ferroptosis by disrupting the DHODH/GPX4 defense system, with the ability to inhibit the growth of resistant tumors and prolong the survival of animal tumor models

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Rosa rugosa polysaccharide induces apoptosis in human cervical cancer cells by inducing autophagy mainly through activating the PI3K/AKT/mTOR pathway (Liu et al., 2022)
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doi: 10.1007/s002280050488
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