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Hold NASO B12 NASAL SPRAY with your thumb on the bottom with your index & middle finger on either side of the nozzle and gently close one side of your nostril with your other index finger

however, the finding of increased cancer risk in shift workers and that patients with neurodegenerative diseases, autism or depression present abnormal melatonin rhythms, have recently increased attention on the role of melatonin

Its implicated in many psychiatric disorders, most notably depression, and is the subject of many psychiatric medications

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While both compounds work through different mechanisms that theoretically could complement each other, the safety, efficacy, and optimal dosing of this combination remain completely unknown
