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noted an antidepressant-like effect on both wildtype and Huntington-disease murine models, which was noted to be due to decreased mitochondrial oxidative stress [33]

10.1111/1750-3841.17529 DATA AVAILABILITY STATEMENT REFERENCES Aguda, R

- **Documentation**: Both the patient and healthcare provider records must include the dose, route (IV infusion), and date of service

however, chronic AMPK activation, continuous mTORC1 inhibition, or a combination of both causes reorganized cytoskeletal structure, lower protein synthesis, increased autophagy, and tubulointerstitial remodeling [113]

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