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This implies that systemic administration of such agents could inadvertently suppress antitumor immunity, canceling out the benefits of ROS-induced tumor killing

Knocking out HIF-1 in osteoclasts inhibits bone resorption and the expression of CT-1

Escobar-Charry, M

Metabolic competence was characterized beforehand

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On the other hand, it is advisable to promote MRD-driven dynamic treatment adjustmentspecifically, within hypomethylating agent plus venetoclax regimenswhere therapy intensity is individualized (escalated or de-escalated) based on serial MRD quantification (via multiparameter flow cytometry or sequencing)