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In this review, we summarize diverse regulatory mechanisms of SLC7A11 in cancer, discuss ferroptosis-dependent and -independent functions of SLC7A11 in promoting tumor development, explore the mechanistic basis of SLC7A11-induced nutrient dependency in cancer cells, and conceptualize therapeutic strategies to target SLC7A11 in cancer treatment
ER stress was also alleviated by impairing either TCA-dependent NADPH production or Glutathione Reductase
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Nutritional deficiencies: Research shows that low levels of iron and zinc can weaken hair and cause hair loss
