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A study found that MRP1 inhibitor can reverse drug resistance related to MRP1 overexpression by decreasing intracellular ATP

Decreased GSH levels increase cellular oxidative stress and are involved in many diseases and conditions, such as cancer, viral infections, and immune dysfunctions

potential role in diseases and therapeutic prospects for the inhibitors
Giustarini et al., 2016

Drug/Gene Co-Delivery MSNs possess the ability to carry small-molecule drugs and nucleic acids (DNA, siRNA, or miRNA) concurrently via surface electrostatic interactions and pore loading [97,212]
