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Foods rich in vitamin C, such as citrus fruits, amla, and bell peppers, help regenerate oxidised glutathione back into its active form

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In brain endothelial cells, Centella extracts have demonstrated protective effects against cytokine-induced barrier disruption and reduced MMP-9mediated permeability, suggesting relevance to bloodbrain barrier preservation in CIRS

For instance, the therapeutic benefits of many natural antioxidants were reported to be associated with their effects to modulate gut microbiota (Shen and Ji, 2019

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