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A prospective, placebo-controlled, randomized, single-blind phase II trial was conducted in a multidisciplinary university hospitals ICU where two groups of patients with systemic inflammatory response syndrome aged more than 18 years were randomized to receive either placebo or intravenous Se as a bolus-loading dosage of 2000 g Se followed by a continuous infusion of 1600 g Se per day for ten days, the study revealed that Se supplementation improved illness severity, and reduces the risk of VAP [90]

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IV therapy earns its place when you need (a) fast rehydration, (b) blood levels you cant hit with pills, (c) reliable absorption when your gut isnt cooperating, or (d) acute symptom relief in a defined situation like a migraine or post-event recovery

doi: 10.1155/2022/4362317 107 WuYHWuYRLi B and YanZY

This has largely restricted our understanding of the function of carnitine in fish, and an explanation of the conflicting results of the application of carnitine in fish remains elusive

On the other hand, I also tell them that we have decades of experience using them, and that they appear to be largely safe and at least anecdotally effective in certain cases