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The original development came from peptide research and the compound retains some peptide-like features

(2005) Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial

As these patients were most likely classified as moderate progressors, the results suggested that 50 mg methylcobalamin injections could be beneficial for patients with ALS in the early stage and with moderate progression rate, the researchers wrote

A set of 27 up-regulated DEGs (TOX (+) versus TOX () condition) was identified as DILI-associated genes within macrophages and dendritic cells highlighting the critical role of innate immune responses in the pathogenesis of drug-induced liver injury (Supplementary Table S1)

Patients may report changes in exercise recovery, energy, focus, or daily performance when therapy is appropriate and well tolerated

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