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2022 Apr;22(2):97-105

However, it should be noted that the analgesic drugs that effectively relieve pain symptoms in CIPN and are used as interventional treatments for pre-existing CIPN-related pain are very limited and that their efficacy in CIPN is significantly lower than that observed in other neuropathic pain types

11, 12, 13, 14, 15 Direct and indirect studies have demonstrated that oxidative stress from reactive oxygen species (ROS) generated through mitochondria, xanthine oxidase, and the NADPH oxidase system 16, 17, 18, 19, 20, 21 is one of the important factors in the pathogenesis of myocardial ischemia

Monitor for interactions: While peptides and GLP-1s work through different mechanisms, individual responses vary

ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway