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A number of compounds in addition to ANIT, including isothiocyanates and isocyanates (e.g., methyl isocyanate), can react reversibly with GSH and thereby be disposed throughout the body (Baillie and Kassahun, 1994)

Dabravolski et al., 2021)

2025;12:e2414734

In support of a possible role for nucleolin in mediating GPx-1 transcript stability, nucleolin has been reported to bind to the 3 UTR of the human GPx-1 transcript (394)

[PubMed: 19501269] (Review of literature on kava hepatotoxicity applying RUCAM scoring for causality to 5 published cases attributed to aqueous and 9 to ethanol-extracted kava, suggesting that liver injury occurs with both)

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