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[PubMed: 19509380] 494

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A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response

The results of both transcriptome and metabolome analysis indicated that blue and red light affected glutathione metabolism mainly in GSSG-GSH cycle, synthesis L-Glutamate to GSH and APX-GSH cycle

Inhibition of these cytokines or surgical removal of the tumor mass can reverse the remodeled immunosuppressive microenvironment, thereby relieving T cell activation constraints and thus enhancing immunotherapy efficacy against circulating DTPs

doi: 10.1002/jsfa.9550