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Description

In addition to its direct antitumor effects, daratumumab exerts an indirect immunomodulatory role by eliminating CD38 + immunosuppressive cell types (Treg, Breg and myeloid-derived suppressor cells) in the tumor microenvironment (TME), thereby promoting T-cell proliferation and effector functions [44]

The results shown in Figure 3 demonstrate the synergistic action of the vitamins B1, B6, and B12, and their superiority vs

2014;74(19_Supplement):5468

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