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Thus, the longer survival of patients with higher IGF-1 levels could be related to direct biological actions of IGF-1, to an overactivation of a protective GH-IGF-1 pathway or to altered IGF-1 levels in patients with a favorable metabolic status

After washing three times with TBS, the sections were stained for 5 min at room temperature with DAPI Nucleic Acid Stain (PA-3013, Lonza, Basel, Switzerland) and washed with TBS

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