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Open J Occup Ther 7(1): 4

Reactive oxygen species are produced by electron leak from aerobic respiration by mitochondria

In addition, these lasting effects can be attributed to maternal inflammation altering the epigenetic machinery of fetal cells and priming the microglia that, as a result, become more responsive to possible stressors afterwards

Influence of eight ABCB1 polymorphisms on antidepressant response in a prospective cohort of treatment-free Russian patients with moderate or severe depression: an explorative psychopharmacological study with naturalistic design

This is possible due to the KEAP1/Nrf2 systems ability to be activated by ROS via oxidation of specific cysteine residues of KEAP1 protein
Perspective: Low Risk of Parkinsons Disease in Quasi-Vegan Cultures May Reflect GCN2-Mediated Upregulation of Parkin