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As shown in the Figure above, at the end of a month, weekly nasal administration results in significantly higher serum Vitamin B12 levels than after intramuscular administration

Nevertheless, one should keep in mind that small changes in DNA methylation (situated on only one or a few not densely packed CGs) might not be detected by genome-wide DNA methylation profiling methods, such as the methyl-cytosine immunoprecipitation and reduced-representation bisulfite sequencing used in the above-mentioned studies (Fouse et al., 2008

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Scientific Background Synthetic peptides have become essential tools in modern biochemical and biomedical research due to their ability to interact selectively with cellular targets

Topical application is simple, requires no medical supervision, and integrates easily into daily skincare routines