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The PINK1/parkin pathway, activated by mitochondrial damage, initiates mitophagy to degrade damaged mitochondria

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There are four recognized TRAIL-Rs: TRAIL-R1, TRAIL-R2, TRAIL-R3, and TRAIL-R4, of which only TRAIL-R1 and TRAIL-R2 are capable of inducing apoptosis

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DAS and its oxidation derivatives DASO and DASO 2 are conjugated with glutathione, in rats (Jin and Baillie, 1997)
