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the other TCAs failed clinical trials for this indication, likely due to insufficient serotonergic activity
Plasma cholesterol, triglycerides, LDL-cholesterol and hepatic GSSG concentrations were measured spectrophotometrically by commercial diagnostic kits (Jiancheng Institute of Biotechnology, Nanjing, China)
Zllig T, Trtzmller M, Kfeler HC
Choosing to use them is essentially a reasoned bet that findings in animal models will translate to humans plausible based on the underlying mechanisms, but not yet proven
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