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However, most thyroid nodules dont cause symptoms

ACTB served as an internal reference gene for this analysis

10.1038/srep24855 78 LiuJ.QuW.KadiiskaM

For example, NAD+-dependent enzymes include the sirtuins (SIRT1-7), a family of protein deacetylases involved in gene expression, stress responses, and metabolic regulation, as well as poly(ADP-ribose) polymerases (PARPs) that assist in DNA repair

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Generally, frameshift and missense mutation are associated with a more severe phenotype of WD [39]
