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Description
This interaction suggests that disruption of the SKI complex, due to factors such as FOCAD (9p21.3) deletion or microsatellite instability-high (MSI-H) status, creates a dependency on PELO and HBS1L for tumor cell Survival
10.1016/s1474-4422(14)70117-6 Lancet Neurol
The CA inhibitors are members of the large sulfonamide class of compounds with the two major drugs in this class being acetazolamide and methazolamide
Using 1 time per week
Safety Assessment Acute toxicity A single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice
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