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(A) Proportional figure showing the total number of peptides in the test dataset, number of peptides with MISPs, number of peptides with MISPs that match to real protein sequences, those which additionally match to multiple distinct sequences, and those which have previously been reported, (B) Number of LCAs per input peptide by input peptide count (C) MISP LCA categories by input peptide count including: LCAs which were different to the input peptides LCA, identical to the input peptides LCA, less taxonomically specific than the input peptides LCA, or more taxonomically specific than the input peptides LCA.

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It is frequently examined in controlled environments to explore pathway-specific activity and cellular response models