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Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance

Diet, gut health, medications, and even genetics influence how efficiently histamine is processed

IGF-1 ASO administration decreased IGF-IR expression in conductance and resistance blood vessels, reduced aortic IGF-1R density, and angiotensin II type 1 receptor expression (208)

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A fascinating study including over 500 patients revealed that IGF-1 concentrations were independently associated with insulin sensitivity accounting for 10.8 % of its variation

Schutte AE, Volpe M, Tocci G, Conti E