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It interacts with GHRH receptors to influence growth hormoneassociated signaling cascades, including pathways linked to IGF-1 production and endocrine feedback regulation

however, its side effects should not be ignored, including asthenia (39.2%) and nausea (43.1%) [152]

Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line

This route offers several advantages: it is easy to perform, relatively painless with proper technique, and provides good systemic absorption

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Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo