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In parallel, we performed gene set variation analysis (GSVA) to compare the level of NRF2 activity in our bulk RNA-sequencing datasets to curated NRF2 gene target signatures consisting of 108 genes from human NSCLC and 207 genes from lymphoblastoid cells (Supplementary Table 1) [30, 31]

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Abstract BTB domain and CNC homolog 1 (BACH1) belongs to the family of basic leucine zipper proteins and is expressed in most mammalian tissues

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