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Expert Opin Emerg Drugs 15:695711 [DOI] [PubMed] [Google Scholar] Sreerama L, Sladek NE

It is implicated in the pathogenesis of Fragile X Syndrome (FXS) and ASD

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Excessive activation of Nrf2 upregulate antioxidant enzymes necessary for the synthesis of GSH, which counterbalance increased ROS formation and thereby does not enable ROS-mediated cell death

M., Lavrijssen B., Gao W., Weijn A., et al

The surgery also changes how the body makes digestive enzymes and bile acids, making nutrient absorption harder
