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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis

It means getting 1000 mcg (1 mg) of B12 injected once a week

Getting vitamins from many dietary sources is always a smart approach

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision

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Ng Published: Endocrinology, Volume 142, Issue 12, December 2001, Pages 51825189 DOI: 10.1210/endo.142.12.8522 URL: Mouse and human cell lines were used to assess 3-adrenergic receptor (3-AR) mRNA expression, protein levels, and function following treatment with AOD9604 and human growth hormone (hGH)