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It also partially activates the expression of GSH, GPX4, and SLC7A11, and inhibits the expression of ROS and IL-18 [156]
However, unlike GPX7, which is a transmembrane protein that contains a C-terminal KEDL endoplasmic reticulum localization sequence and a highly conserved N-terminal transmembrane domain (TMD) (Yoboue et al., 2017)
IL-17, which has a variable inflammatory effect that promotes the migration of inflammatory cells to inflammatory tissues, levels of IL-17 were found to decrease in lung homogenates of fibrotic mice treated with vitamin C (126)
Periplasmic protein thiol:disulfide oxidoreductases of Escherichia coli
PMID: 21777251
Figure 5D and Table 2)
