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Exploring Pharmacological Mechanisms of Lavender (Lavandula angustifolia) Essential Oil on Central Nervous System Targets

in fibroblast culture models it stimulates collagen, elastin, and glycosaminoglycan synthesis at picomolar to nanomolar concentrations (10 to 10 M), and modulates metalloproteinase (MMP-1, MMP-2, MMP-9) activity and their inhibitors (TIMP-1, TIMP-2), functioning as a general regulator of extracellular matrix remodeling ( Mechanistic research establishes that GHK activates TGF- and integrin 1 pathways during tissue repair, attracts immune and endothelial cells to wound sites, and restores gene expression patterns toward a healthier fibroblast phenotype in models of aging and radiation damage ( A 2018 review in IJMS characterizes its role in collagen production, nerve outgrowth stimulation, and dermal stem cell marker expression ( For Research Use Only

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In physician-supervised practice, it is one of the most frequently prescribed regenerative peptides, used for joint and tendon injury, sports rehabilitation, post-surgical recovery, and gut healing

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[DOI] [PubMed] [Google Scholar] 7.Seiwerth S., Rucman R., Turkovic B., Sever M., Klicek R., Radic B., Drmic D., Stupnisek M., Misic M., Vuletic L.B., et al