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In 2010, a randomised, placebo-controlled trial was published in the BMJ
The GH/IGF-1 axis in obesity: physiological and pathological aspects

Defyne is better for areas where your natural tissue is firmer
Id say the effect lasted about 24 hours

The standard dosage ranges from 300-500mcg daily, often taken in the morning on an empty stomach to maximize fat-burning effects
Esomeprazole should be taken at least 1 hour before meals