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Excess ROS then activates the NLRP3 inflammasome in microglia, promoting maturation and release of IL-1 ( 4.3 GSH metabolism: a central hub in mid-late SAE The hippocampus, with its high metabolic demands and low antioxidant capacity, is uniquely vulnerable to septic injury ( A Stat1-Gpx3 hub was identified, where TNF-/IL-1-induced Stat1 activation suppresses Nrf2 (confirmed by reduced hippocampal Nrf2)

doi: 10.22088/cjim.13.0.264 82 RaveendranA

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Pontarollo, G

Vitamin E has been considered an essential nutrient since 1968, although it has been known as a dietary component since the 1920s

Types and chromosomal locations of the ALP gene with their accession numbers are shown in Table 1