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Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N et al

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To validate whether the approach can solubilize proteins from the active zone, the authors introduced TurboID into the endogenous ELKS-1 gene, which encodes a presynaptic active zone protein

Bringing any drug through Phase II and Phase III to regulatory approval costs hundreds of millions