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Indeed, using the exact same paradigm, interactions between the OFC and amygdala in marmosets have been shown to contribute to the long-lasting mnemonic effects of punishment on decision making, without influencing decision making at the time of punishment per se [149]

The evidence base was dominated by preclinical animal and mechanistic investigations, while human clinical outcome data were limited and largely observational

[33] In a proof-of-concept study, zoledronic acid, a bisphosphonate commonly used in treatment of osteosarcoma and cancer-induced osteoporosis, was found to be senolytic and senomorphic under in vivo conditions
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10.1038/scientificamerican0716-46
