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BPC157 0.5 g (0.35 mmol) BPC157 was dissolved in 10 ml of methanol containing 42.6 mg (0.35 mmol) of tris-(hydroxymethyl)-aminomethane (TRIS), sterile filtered through a 0.2 filter and dried by evaporation of methanol in a vacuum at 40C to obtain 0.56 g of white solid
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We further modified 1907 by N -myristoylation to identify an optimized lead peptide (2012) with improved cell permeability, drug metabolism, pharmacokinetic (DMPK) properties, and in vitro efficacy

characterised its broad gene regulatory effects across skin remodeling pathways
Author contributions K.Y., K.S.V., S.J., T.C.M.T., and V.S.: resourcing, table creation, and writing the original draft
