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Loffredo FS, Pancoast JR, Cai L, Vannelli T, Dong JZ, Lee RT, et al

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Citrulline source also appears influential: pure L-citrulline supplements typically provided higher daily doses (610 g) and showed more consistent vascular benefits, whereas watermelon products delivered lower citrulline equivalents (1.52.3 g/day) and yielded mixed results, possibly due to additional bioactive compounds (e.g., lycopene, vitamin C) exerting independent effects