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Retrieved June 8, 2025, from Rigg, L

Multi-site or diffuse injuries: Patients with two or more active injury sites, or with a diffuse pattern of soft tissue damage that is not localized to a single structure

Increased stress can directly damage the disc, disrupt intradiscal pressure balance, and cause structural alterations
10.1038/srep23229 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.De Geyter C

Researchers have found that our natural NAD+ stores get lower as we get older, which is why older adults may benefit from higher or more consistent NAD supplementation

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