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Main methods Assessment included magnesium sulfate (560 mg/kg intraperitoneally)-induced muscle weakness, muscle and brain lesions, hypermagnesemia, hyperkalaemia, increased serum enzyme values assessed in rats during and at the end of a 30-min period and medication (given intraperitoneally/kg at 15 min before magnesium) [BPC 157 (10 g, 10 ng), l-NAME (5 mg), l-arginine (100 mg), alone and/or together]

Manalo, T.E

The important question of timing of drug treatment has become more high profile in the clinic with the individualization of treatment regimes especially for cancer and the melatonin rhythm might well provide an individual circadian marker for timing specification (201)

E., Battie, M

V.kuljecJ.GudiV.SkripuletzT.PulR.TrebstC.et al

Adhesion-mediated Multiple Myeloma (MM) Disease Progression: Junctional Adhesion Molecule a Enhances Angiogenesis and Multiple Myeloma Dissemination and Predicts Poor Survival