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Mechanisms underlying the effects of metformin in lung cancer treatment Metformin has been the safest and most widely prescribed drug for type 2 diabetes (T2D) (35)

M.FrisardiV.SantamatoA.RanieriM.FioreP.VendemialeG.SeripaD.PilottoA.CapursoA.SolfrizziV

Other causes included statins, NSAIDs, antiretroviral therapies, and non-TB antibiotics

Tumors driven by oncogenes such as c-Myc or KRAS exhibit a marked dependence on exogenous glutamine, underscoring its potential as a therapeutic target and a promising biomarker for diagnostic imaging

pp 137151 Pettegrew JW, Nichols JS, Minshew NJ, Rush AJ, Stewart RM
