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Common symptoms of homocystinuria are dislocated optic lenses (ectopia lentis), osteoporosis, lengthening and thinning of the long bones, and an increased risk of abnormal blood clotting (thromboembolism)

In elderly patients with depression, a recent cross-sectional study revealed that reduced abundance of Akkermansia in the gut microbiota leads to increased levels of free fatty acids (FFA), contributing to cognitive decline (170) ( Figure 1A )

In particular, as for the medicinal part, the antlers of P

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GPX4 inhibition activated ferroptosis, inducing TC cell death, rapid rise in reactive oxygen species and effectively arrested cell migration in vitro

This section summarizes current research progress on mitochondrial biogenesis, mitophagy, and mitochondrial dynamics in common neurodegenerative diseases (AD, PD, HD, and ALS) (Figure 5)