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[DOI] [PMC free article] [PubMed] [Google Scholar] Manzer Z

Morgenstern, R., Zhang, J

The effect of mitochondrial transplantation therapy from different gender on inhibiting cell proliferation of malignant melanoma

Lakowicz and Gregorio Weber reported that despite their common location in the interior of the protein matrix and the apparent inaccessibility to solvent, no tryptophan residues were excluded from quenching by oxygen (which is an ideal quencher of the fluorescence of singlet excited states, as every collision with an excited fluorophore results in quenching), indicating that proteins, in general, undergo rapid structural fluctuations on the nanosecond time scale which permit diffusion of oxygen (Lakowicz and Weber, 1973)