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Patients with inborn errors of metabolism or genetic variants of enzymes involved in VPA metabolism appear to be at risk of developing hepatotoxicity

Pregabalin for neuropathic pain in adults

Haemodialysis and haemodiafiltration can both reach clearance rates of 90 mL/min whilst low flow continuous renal replacement techniques achieve a clearance rate of only between 10 and 15 mL/min

Beggs S, Trang T, Salter MW

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